Table 20.
Frequency and respective percentage of mutations detected in each invariant residue window of ORF3a, ORF6, ORF7a, ORF7b, and ORF8 proteins.
| Number of mutations | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Protein | Invariant residues | Tunisia | Texas | Spain | Serbia | Poland | Peru | Pennsylvania | Pakistan | Minnesota | Michigan | Massachusetts | India |
| ORF3a | 31–36 | 0 | 5 | 0 | 1 | 0 | 0 | 6 | 0 | 6 | 5 | 5 | 1 |
| ORF3a | 53–58 | 1 | 5 | 2 | 2 | 2 | 1 | 6 | 1 | 4 | 5 | 6 | 4 |
| ORF3a | 135–142 | 0 | 4 | 1 | 0 | 0 | 0 | 4 | 1 | 5 | 2 | 8 | 0 |
| ORF3a | 154–162 | 1 | 9 | 0 | 1 | 1 | 0 | 4 | 0 | 9 | 9 | 9 | 1 |
| ORF3a | 244–255 | 0 | 12 | 1 | 0 | 1 | 3 | 7 | 2 | 12 | 12 | 6 | 3 |
| ORF3a | 262–275 | 0 | 13 | 0 | 0 | 0 | 0 | 14 | 0 | 12 | 13 | 12 | 1 |
| Protein | Invariant residues | Hong Kong | Greece | Ghana | France | Florida | Egypt | Chile | California | Bangladesh | Bahrain | Austria | Australia |
| ORF3a | 31–36 | 0 | 1 | 0 | 1 | 6 | 3 | 1 | 6 | 0 | 1 | 1 | 2 |
| ORF3a | 53–58 | 1 | 1 | 2 | 1 | 5 | 3 | 1 | 6 | 3 | 1 | 1 | 5 |
| ORF3a | 135–142 | 0 | 0 | 0 | 0 | 8 | 0 | 1 | 8 | 1 | 1 | 0 | 7 |
| ORF3a | 154–162 | 0 | 1 | 1 | 1 | 9 | 2 | 0 | 9 | 1 | 0 | 0 | 9 |
| ORF3a | 244–255 | 1 | 6 | 0 | 1 | 12 | 3 | 1 | 11 | 3 | 0 | 0 | 4 |
| ORF3a | 262–275 | 1 | 0 | 0 | 0 | 13 | 1 | 0 | 14 | 2 | 1 | 0 | 5 |
| Protein | Invariant residues | Tunisia | Texas | Spain | Serbia | Poland | Peru | Pennsylvania | Pakistan | Minnesota | Michigan | Massachusetts | India |
| ORF6 | 1–15 | 0 | 13 | 0 | 0 | 0 | 0 | 7 | 1 | 13 | 11 | 12 | 3 |
| Protein | Invariant residues | Hong Kong | Greece | Ghana | France | Florida | Egypt | Chile | California | Bangladesh | Bahrain | Austria | Australia |
| ORF6 | 1–15 | 0 | 0 | 2 | 1 | 11 | 0 | 1 | 14 | 4 | 11 | 1 | 12 |
| Protein | Invariant residues | Tunisia | Texas | Spain | Serbia | Poland | Peru | Pennsylvania | Pakistan | Minnesota | Michigan | Massachusetts | India |
| ORF7a | 15–31 | 0 | 13 | 0 | 0 | 0 | 2 | 9 | 1 | 8 | 11 | 15 | 1 |
| ORF7a | 37–58 | 0 | 22 | 1 | 1 | 3 | 8 | 19 | 1 | 20 | 22 | 21 | 2 |
| ORF7a | 75–93 | 0 | 19 | 0 | 1 | 0 | 0 | 19 | 1 | 19 | 19 | 19 | 3 |
| Protein | Invariant residues | Hong Kong | Greece | Ghana | France | Florida | Egypt | Chile | California | Bangladesh | Bahrain | Austria | Australia |
| ORF7a | 15–31 | 0 | 0 | 1 | 0 | 9 | 2 | 1 | 17 | 4 | 1 | 0 | 5 |
| ORF7a | 37–58 | 1 | 0 | 1 | 0 | 22 | 1 | 1 | 22 | 3 | 2 | 1 | 9 |
| ORF7a | 75–93 | 0 | 0 | 1 | 0 | 19 | 4 | 0 | 19 | 3 | 3 | 1 | 8 |
| Protein | Invariant residues | Tunisia | Texas | Spain | Serbia | Poland | Peru | Pennsylvania | Pakistan | Minnesota | Michigan | Massachusetts | India |
| ORF7b | 6–25 | 0 | 14 | 0 | 0 | 0 | 0 | 12 | 1 | 13 | 18 | 17 | 5 |
| ORF7b | 27–33 | 0 | 5 | 0 | 0 | 0 | 0 | 4 | 0 | 3 | 4 | 5 | 1 |
| Protein | Invariant residues | Hong Kong | Greece | Ghana | France | Florida | Egypt | Chile | California | Bangladesh | Bahrain | Austria | Australia |
| ORF7b | 6–25 | 0 | 0 | 8 | 0 | 17 | 3 | 0 | 19 | 1 | 1 | 0 | 12 |
| ORF7b | 27–33 | 0 | 0 | 4 | 0 | 5 | 2 | 0 | 6 | 2 | 0 | 0 | 2 |
| Protein | Invariant residues | Tunisia | Texas | Spain | Serbia | Poland | Peru | Pennsylvania | Pakistan | Minnesota | Michigan | Massachusetts | India |
| ORF8 | 35–38 | 0 | 2 | 0 | 0 | 1 | 0 | 2 | 0 | 4 | 4 | 4 | 0 |
| ORF8 | 88–91 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 2 | 0 |
| Protein | Invariant residues | Hong Kong | Greece | Ghana | France | Florida | Egypt | Chile | California | Bangladesh | Bahrain | Austria | Australia |
| ORF8 | 35–38 | 0 | 0 | 4 | 1 | 4 | 1 | 0 | 4 | 1 | 1 | 0 | 1 |
| ORF8 | 88–91 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 4 | 0 | 0 | 0 | 0 |