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. 2022 Sep 26;2022(9):CD011642. doi: 10.1002/14651858.CD011642.pub2

Maari 2017.

Methods Randomised, controlled, within‐patient, single‐blinded, pilot study
Participants Burn hypertrophic scars
Interventions Laser treatment on burn HSc relative to self‐matched control scars in 12 patients. The randomly selected scars were treated with the CORE fractional CO2 laser (Candela/Syneron, Mississauga, ON) with the Fusion Mode at the following settings: 25% fractional coverage, ring energy of 17.9 J/cm2, CORE energy of 311 J/cm2 for 2 passes/treatment session.
Outcomes Scar pliability, thickness, vascularity, pain, itch and patient satisfaction. Each site were measured using the Cutometer, Mexameter, and high‐frequency ultrasound at baseline, immediately prior to the 3rd treatment and 12 weeks after the final treatment.
Notes This study did not show a statistical difference between laser treated scar and control in erythema (P .3), pliability (P .2), or thickness (P.4). Larger studies are needed to further evaluate fractional laser as a treatment modality for burn victims.
Reported as abstract. No clear description of the control arm (if active ‐ with or without laser or inactive control).

HSc hypertrophic scar.