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. 2022 Sep 21;15:5575–5587. doi: 10.2147/IDR.S380137

Figure 4.

Figure 4

Intersectional gene analysis. (A) PPI network showing light green for myeloid leukocyte activation, purple for neutrophil degranulation, yellow for inflammatory response, pink for cell activation, dark green for immune system process, dark yellow represents secretory granule, red represents extended region, and royal blue represents vesicle. (B) heat map with purple for high expression in sepsis group and green for low expression in sepsis group; sample number below and gene name on the right; color shades respond to high and low expression values. (C) BP shows that the intersecting genes are mainly enriched in myeloid leukocyte activation, exocytosis, cell activation, neutrophil mediated immunity, secretion by cell, neutrophil activation, cell activation involved in immune response. (D) CC shows that the intersecting genes are mainly located in extracellular space, extracellular exosome, extracellular vesicle, secretory vesicle. (E), MF indicates that these genes are mainly involved in lactate dehydrogenase activity, oxidoreductase activity, signaling receptor activator activity, receptor ligand activity and other molecular processes. The darker nodes are the more significant enriched gene sets, and the larger nodes represent a larger number of enriched gene sets.