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. 2022 Sep 8;10:994412. doi: 10.3389/fcell.2022.994412

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Copyright © 2022 Krueger and Morris.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Vertebrate Ocular Development. Schematic representation of ocular development stages from eye field specification to bi-layered optic cup formation (A–E). This process occurs between 12 and 24 hpf in zebrafish, E8-10 in mouse, and from ∼4 to 7 weeks in human. See text for process details. EF, eye field; N, notochord; OV; optic vesicle; LP, lens placode/pit; POM, periocular mesenchyme; RPE, retinal pigment epithelium; NR, neural retina; L, lens. Figure created with Biorender.com.