Table 1.
Baseline characteristics of the participants in the placebo and curcumin groups
| Placebo | Curcumin | P-value | |||
|---|---|---|---|---|---|
| n | Data | n | Data | ||
| Sex (M/F) | 69 | 56/13 | 73 | 58/15 | 0.836 |
| Age, years old | 69 | 66.0 (59.5–73.0) | 72 | 67.0 (59.0–73.8) | 0.816 |
| BMI, kg/m2 | 68 | 26.2 (23.8–28.8) | 69 | 26.6 (24.0–29.1) | 0.605 |
| SBP, mmHg | 68 | 131.5 (119.3–141.0) | 71 | 130.0 (122.0–144.0) | 0.606 |
| DBP, mmHg | 68 | 75.0 (69.0–81.0) | 71 | 75.0 (69.0–83.0) | 0.859 |
| Pulse, b.p.m. | 68 | 73.3 ± 11.8 | 71 | 73.3 ± 13.1 | 0.999 |
| Cre, mg/dL | 65 | 0.85 (0.80–0.98) | 66 | 0.88 (0.74–1.01) | 0.980 |
| BNP, pg/mL | 64 | 10.9 (6.1–35.5) | 63 | 12.7 (6.0–27.9) | 0.809 |
| LAD, mm | 69 | 38.8 ± 5.1 | 72 | 38.6 ± 5.1 | 0.823 |
| LVDd, mm | 69 | 47.3 ± 4.3 | 72 | 47.1 ± 5.0 | 0.835 |
| EF, % | 69 | 67.0 (63.5–69.0) | 72 | 67.0 (63.3–69.8) | 0.437 |
| IVS, mm | 69 | 11.0 (11.0–11.5) | 72 | 11.0 (10.0–11.0) | 0.115 |
| PWT, mm | 69 | 11.0 (11.0–11.0) | 72 | 11.0 (11.0–11.0) | 0.575 |
| E/A | 69 | 0.81 (0.69–0.93) | 72 | 0.85 (0.73–0.99) | 0.142 |
| DcT, ms | 68 | 233.0 (208.8–267.8) | 72 | 237.0 (206.5–262.5) | 0.993 |
| E/E′ | 68 | 11.4 (10.3–13.7) | 72 | 11.7 (10.3–13.7) | 0.871 |
| Past history | |||||
| Cardiovascular disease | 69 | 46 | 73 | 56 | 0.203 |
| DM | 69 | 33 | 73 | 26 | 0.173 |
| COPD | 69 | 24 | 73 | 25 | >0.999 |
| Cancer | 69 | 16 | 73 | 11 | 0.285 |
| Medication | |||||
| RA inhibitors | 69 | 57 | 73 | 50 | 0.084 |
| Beta-blockers | 69 | 16 | 73 | 8 | 0.039 |
| Vasodilators | 69 | 7 | 73 | 3 | 0.316 |
| Statins | 69 | 40 | 73 | 43 | >0.999 |
| Any anti-DM drugs | 69 | 23 | 73 | 22 | 0.721 |
| Any antithrombotic drugs | 69 | 24 | 73 | 26 | >0.999 |
Data are presented as the mean ± SD for parametric data or as median (interquartile range) for non-parametric data. Bold values indicate P < 0.05, which means ‘significant’.
BMI, body mass index; BNP, brain natriuretic peptide; COPD, chronic obstructive pulmonary disease; Cre, creatinine; DBP, diastolic blood pressure; DcT, deceleration time; EF, ejection fraction; IVS, interventricular septum; LAD, left axis deviation; LVDd, left ventricular end-diastolic diameter; PWT, posterior LV wall thickness; SBP, systolic blood pressure.