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. 2022 Sep 10;2(5):oeac057. doi: 10.1093/ehjopen/oeac057

Table 2.

Per cent changes of parameter in each group

Placebo Curcumin P-value Mean difference 95% CI Cohen’s d
n % change n % change
Δ BMI (%) 62 0.0 (−1.7, 1.3) 58 0.0 (−1.6, 1.7) 0.823 −0.1 −1.2, 1.0 0.03
Δ SBP (%) 67 0.0 (−4.5, 9.9) 68 −3.4 (−8.1, 3.3) 0.026 −4.2 −7.9, −0.4 0.38
Δ DBP (%) 67 1.1 (−7.0, 10.9) 68 −1.4 (−8.1, 7.4) 0.386 −1.6 −6.3, 3.1 0.11
Δ pulse (%) 67 −1.1 (−8.4, 6.3) 68 0.0 (−10.8, 10.8) 0.336 3.8 −1.4, 8.9 0.25
Δ Cre (%) 64 0.4 (−5.9, 6.8) 63 0.0 (−4.8, 5.6) 0.630 1.2 −2.5, 4.8 0.11
Δ BNP (%) 62 5.0 (−7.1, 58.5) 60 0.0 (−26.8, 42.1) 0.032 −34.7 −63.9, −5.5 0.43
Δ LAD (%) 67 0.0 (−7.5, 5.4) 70 0.0 (−7.9, 6.1) 0.935 0.0 −3.7, 3.7 0.00
Δ LVDd (%) 67 0.0 (−2.4, 4.5) 70 0.0 (−4.4, 3.9) 0.253 −1.0 −3.3, 1.4 0.14
Δ EF (%) 67 −1.4 (−7.2, 4.5) 70 −1.5 (−7.3, 3.7) 0.814 −0.2 −3.3, 3.0 0.02
Δ IVS (%) 67 0.0 (−8.3, 0.0) 69 0.0 (−8.3, 0.0) 0.403 1.6 −1.9, 5.1 0.15
Δ PWT (%) 67 0.0 (−8.3, 0.0) 69 0.0 (−9.1, 0.0) 0.662 −0.5 −3.5, 2.4 0.06
Δ E/A (%) 67 −3.8 (−13.9, 11.8) 69 −6.1 (−16.0, 10.7) 0.531 −2.5 −9.7, 4.8 0.11
Δ DcT (%) 66 −1.1 (−14.8, 9.8) 69 −2.9 (−15.6, 20.0) 0.490 6.6 −2.8, 15.9 0.24
ΔE/E′ (%) 66 −3.6 ± 21.7 69 −2.7 ± 22.8 0.833 0.8 −6.8, 8.4 0.04

Data are presented as the mean ± SD for parametric data or as median (interquartile range) for non-parametric data. Bold values indicate P < 0.05, which means ‘significant’.

Abbreviations used in this table are the same as in Table 1.