Table 2.
Placebo | Curcumin | P-value | Mean difference | 95% CI | Cohen’s d | |||
---|---|---|---|---|---|---|---|---|
n | % change | n | % change | |||||
Δ BMI (%) | 62 | 0.0 (−1.7, 1.3) | 58 | 0.0 (−1.6, 1.7) | 0.823 | −0.1 | −1.2, 1.0 | 0.03 |
Δ SBP (%) | 67 | 0.0 (−4.5, 9.9) | 68 | −3.4 (−8.1, 3.3) | 0.026 | −4.2 | −7.9, −0.4 | 0.38 |
Δ DBP (%) | 67 | 1.1 (−7.0, 10.9) | 68 | −1.4 (−8.1, 7.4) | 0.386 | −1.6 | −6.3, 3.1 | 0.11 |
Δ pulse (%) | 67 | −1.1 (−8.4, 6.3) | 68 | 0.0 (−10.8, 10.8) | 0.336 | 3.8 | −1.4, 8.9 | 0.25 |
Δ Cre (%) | 64 | 0.4 (−5.9, 6.8) | 63 | 0.0 (−4.8, 5.6) | 0.630 | 1.2 | −2.5, 4.8 | 0.11 |
Δ BNP (%) | 62 | 5.0 (−7.1, 58.5) | 60 | 0.0 (−26.8, 42.1) | 0.032 | −34.7 | −63.9, −5.5 | 0.43 |
Δ LAD (%) | 67 | 0.0 (−7.5, 5.4) | 70 | 0.0 (−7.9, 6.1) | 0.935 | 0.0 | −3.7, 3.7 | 0.00 |
Δ LVDd (%) | 67 | 0.0 (−2.4, 4.5) | 70 | 0.0 (−4.4, 3.9) | 0.253 | −1.0 | −3.3, 1.4 | 0.14 |
Δ EF (%) | 67 | −1.4 (−7.2, 4.5) | 70 | −1.5 (−7.3, 3.7) | 0.814 | −0.2 | −3.3, 3.0 | 0.02 |
Δ IVS (%) | 67 | 0.0 (−8.3, 0.0) | 69 | 0.0 (−8.3, 0.0) | 0.403 | 1.6 | −1.9, 5.1 | 0.15 |
Δ PWT (%) | 67 | 0.0 (−8.3, 0.0) | 69 | 0.0 (−9.1, 0.0) | 0.662 | −0.5 | −3.5, 2.4 | 0.06 |
Δ E/A (%) | 67 | −3.8 (−13.9, 11.8) | 69 | −6.1 (−16.0, 10.7) | 0.531 | −2.5 | −9.7, 4.8 | 0.11 |
Δ DcT (%) | 66 | −1.1 (−14.8, 9.8) | 69 | −2.9 (−15.6, 20.0) | 0.490 | 6.6 | −2.8, 15.9 | 0.24 |
ΔE/E′ (%) | 66 | −3.6 ± 21.7 | 69 | −2.7 ± 22.8 | 0.833 | 0.8 | −6.8, 8.4 | 0.04 |
Data are presented as the mean ± SD for parametric data or as median (interquartile range) for non-parametric data. Bold values indicate P < 0.05, which means ‘significant’.
Abbreviations used in this table are the same as in Table 1.