Figure 5.

Photographs of 3 patients with Cushing’s syndrome, illustrating the range of physical features. The man on the left demonstrates central obesity, striae, supraclavicular fullness, rounded face with filling of the temporal fossae, and poor skin healing (bandage). The woman in the middle has increased supraclavicular fullness, facial plethora, and a history of new hypertension and depression. The woman on the right appears normal except for some facial fullness in comparison to previous photographs. By history, she was gained weight, with increased abdominal girth, and a history of mild decreases in cognition and short-term recall (memory).