Table 7.

Predictive Value of Lac, Age and SOFA Score in Predicting 28-Day Mortality in Patients with Sepsis

Independent Predictors	AUC	95% CI		P value	Cutoff	Sensitivity	Specificity	Youden Index	Positive Likelihood Ratio	Negative Likelihood Ratio
Age	0.626	0.461	0.791	0.149	80.5	0.706	0.674	0.38	2.166	0.436
SOFA	0.747	0.606	0.889	0.005**	2.5	0.941	0.13	0.071	1.082	0.454
Lac	0.679	0.524	0.834	0.040*	1.7	0.688	0.649	0.337	1.96	0.481
SOFA+Lac	0.748	0.607	0.889	0.004**	0.247	0.875	0.676	0.551	2.701	0.185
SOFA+ Age	0.785	0.656	0.915	0.001**	0.466	0.588	0.891	0.479	5.394	0.462
Lac+ Age	0.711	0.558	0.864	0.015*	0.281	0.813	0.568	0.381	1.882	0.329
SOFA+Lac+ Age	0.819	0.694	0.945	0.000***	0.44	0.625	0.892	0.517	5.787	0.42

Notes: *Means p < 0.05, **Means p < 0.01, ***Means p < 0.001.

Abbreviations: SOFA, Sequential Organ Failure Assessment; Lac, lactate; CI, confidence interval.