Appendix 1—table 3. Predictors of partial/complete pathologic response following neoadjuvant chemotherapy in resected patients with localized pancreatic ductal adenocarcinoma using multivariable logistic regression.

Variable	OR (95% CI)	P-value
Age	1.02 (0.92, 1.09)	0.68
Gender Female Male	Ref 2.86 (0.45, 26.2)	- 0.34
Diagnosis BMI	0.88 (0.74, 1.08)	0.21
CA 19–9 dynamics Any increase Any decrease	Ref 1.82 (0.001, 3.74)	- 0.05
Resectability Status Borderline Locally advanced Resectable	Ref 2.72 (0.22, 33.2) 0.64 (0.06, 7.44)	- 0.43 0.72
Radiographic tumor size	0.98 (0.91, 1.05)	0.54
NAC duration (months)	1.09 (0.68, 1.75)	0.73
Absolute pre-chemotherapy aNLR Low High	Ref 0.02 (0.003, 0.15)	<0.001
ΔNLR Low High	Ref 0.06 (0.01, 0.33)	0.002