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. 2022 Jul 22;20(3):90–92. doi: 10.1002/cld.1236

TABLE 2.

Medications and therapies used to treat HE

Therapy How it works Goal
Lactulose Laxative (causes frequent bowel movements that make you “poop out” the ammonia from your body) First line to treat HE
Goal is to have 3–4 loose bowel movements per day
May cause bloating
Rifaximin Antibiotic not absorbed from the gut Use with lactulose
Take one tablet twice a day
Nutrition High‐calorie and ‐protein meals to maintain muscle Goal is to build muscle, which helps process ammonia, because many patients with cirrhosis lose muscle