Date	Event	Description
7 May 2021	New citation required and conclusions have changed	Summary of most important changes when compared to second update: The original review was split and this part now focuses on dexrazoxane only. We analysed adult and paediatric data separately. New randomised controlled trials and additional data on some already included studies were added. We updated the risk of bias criteria. In previous versions of the review, best‐case analyses were performed; starting with this update we present results from available‐case, best‐case and worst‐case analyses where possible.
7 May 2021	New search has been performed	The search for eligible studies was updated to 7 May 2021.