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. 2022 Sep 27;2022(9):CD014638. doi: 10.1002/14651858.CD014638.pub2

Jackowska 2003.

Methods Unclear if this is a randomised controlled trial.
Participants 107 children (age nm; sex nm) with acute lymphoblastic leukaemia (stage nm) treated with either doxorubicin or daunorubicin containing therapy (cumulative dose 120 mg/m2; peak dose (i.e. maximal dose received in 1 week) nm; infusion duration nm). Prior anthracycline therapy nm. Prior cardiac radiotherapy nm. Prior cardiac dysfunction nm.
Interventions Dexrazoxane (ratio to anthracycline nm; timing in relation to anthracycline nm) (N = 43) versus no cardioprotective intervention (N = 64).
Outcomes Toxicities other than cardiotoxicity.
Notes Unclear if this is an ongoing or completed study. Unclear if cardiotoxicity is evaluated in this study. Length of follow‐up nm. Cumulative anthracycline dose per treatment group nm. Age per treatment group nm.