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. 2022 Sep 20;3(9):100659. doi: 10.1016/j.xcrm.2022.100659

Figure 2.

Figure 2

MET and AXL are overexpressed in patient tumors following relapse after cisplatin plus irradiation and correlate with poor prognosis

(A) The levels of MET and AXL mRNAs in healthy tissue and in HNSCC (TCGA cohort) were compared.

(B) The levels of MET and AXL mRNA (qRT-PCR) in HNSCC at diagnosis were compared with the levels in HNSCC after relapse on cisplatin plus irradiation (paired samples for each patient at diagnosis and relapse, French cohort, see Table S1).

(C–F) The levels of MET (C and E) and AXL (D and F) mRNA in HNSCC patients (diagnosis) from the French (C and D) and the TCGA cohorts (E and F) correlated with OS. The Kaplan-Meier method was used to produce survival curves and analyses of censored data were performed using Cox models. Statistical significance (p values) is indicated.