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. 2022 Aug 11;40(10):2411–2422. doi: 10.1007/s00345-022-04124-x

Table 3.

Cumulative Incidence of GU toxicity admission with competing risk regression including overall mortality

Group Characteristic Years 5 Years 10 p value1
GU toxicity Age ≥ 70 years 0.017
   Older 16% (14%, 17%) 26% (24%, 29%)
   Younger 12% (10%, 14%) 23% (20%, 25%)
Mortality Age ≥ 70 years < 0.001
   Older 13% (12%, 15%) 32% (29%, 35%)
   Younger 8.0% (6.5%, 9.7%) 21% (18%, 24%)
GU toxicity Diabetes Mellitus
   Absent 13% (11%, 14%) 22% (20%, 24%) < 0.001
   Present 20% (16%, 23%) 34% (29%, 38%)
Mortality Diabetes Mellitus 0.3
   Absent 11% (9.7%, 12%) 26% (24%, 28%)
   Present 12% (9.1%, 15%) 31% (26%, 35%)
GU toxicity Smoking history < 0.001
   Non-smoker 8.3% (6.9%, 9.8%) 15% (13%, 17%)
   Smoker 20% (18%, 22%) 35% (32%, 38%)
Mortality Smoking history 0.2
   Non-smoker 11% (9.8%, 13%) 27% (25%, 30%)
   Smoker 11% (9.2%, 13%) 27% (24%, 29%)
GU toxicity BOO and TURP prior to EBRT < 0.001
   No 11% (9.5%, 12%) 20% (18%, 22%)
   Yes 37% (32%, 42%) 56% (50%, 61%)
Mortality BOO and TURP prior to EBRT < 0.001
   No 11% (9.7%, 12%) 28% (26%, 30%)
   Yes 13% (9.5%, 17%) 19% (15%, 24%)
GU toxicity BOO without TURP before EBRT < 0.001
   No 12% (10%, 13%) 20% (18%, 22%)
   Yes 43% (36%, 50%) 77% (70%, 82%)
Mortality BOO without TURP before EBRT < 0.001
   No 12% (11%, 13%) 29% (27%, 31%)
   Yes 3.8% (1.8%, 7.0%) 3.8% (1.8%, 7.0%)
GU toxicity EBRT ≥ 2009 < 0.001
   After 12% (10%, 14%) 19% (16%, 21%)
   Before 17% (15%, 19%) 29% (26%, 31%)
Mortality < 0.001
   After 13% (11%, 14%) 39% (33%, 46%)
   Before 10.0% (8.4%, 12%) 23% (21%, 26%)

Any statistically significant p-values were bolded