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. 2022 Sep 26;12:16041. doi: 10.1038/s41598-022-20302-8

Table 3.

Association between socio-demographic and medical parameters and all-cause mortality rates from stroke types for the years 2014–2019.

Variable Acute Ischemic Stroke Intracerebral Hemorrhage Subarachnoid Hemorrhage
Frequency/dead, N/n (%) HR (95% CI) p value Frequency/dead, N/n (%) HR (95% CI) p value Frequency/dead, N/n (%) HR (95% CI) p value
Demographics
Age category (< 18 y.o. (ref))
18–34 y.o 1,809/165 (9) 1.08 (0.75;1.54) 0.696 809/ 200 (25) 1.24 (1.02;1.52) 0.034 329/73 (22) 1.76 (1.24;2.49) 0.001
35–50 y.o 14,040/18,99 (14) 1.86 (1.34;2.59)  < 0.001 5,645/1,888 (33) 2.04 (1.75;2.37)  < 0.001 1 173/336 (29) 2.81 (2.11;3.73)  < 0.001
51–70 y.o 75,434/19,076 (25) 3.71 (2.67;5.14)  < 0.001 19,350/7,286 (38) 2.32 (1.99;2.69)  < 0.001 2 512/928 (37) 4.07 (3.1;5.35)  < 0.001
 > 70 y.o 46,833/23,233 (50) 8.15 (5.87;11.3)  < 0.001 7,560/4,261 (56) 3.37 (2.9;3.92)  < 0.001 726/439 (60) 6.6 (4.98;8.75)  < 0.001
Gender (Male vs Female (ref)) 72,584/22,431 (31) 1.12 (1.1;1.14)  < 0.001 18,603/7,352 (40) 1.03 (0.99;1.07) 0.052 2 505/909 (36) 1.1 (1.01;1.21) 0.038
Ethnicity (Kazakh (ref))
Russian 41,978/17,481 (42) 1.53 (1.49;1.57)  < 0.001 7,191/3,728 (52) 1.42 (1.36;1.48)  < 0.001 1,020/446 (44) 1.29 (1.15;1.45)  < 0.001
Other 26,347/8,969 (34) 1.18 (1.15;1.21)  < 0.001 5,403/2,236 (41) 1.05 (0.99;1.1) 0.059 810/315 (39) 1.07 (0.94;1.21) 0.303
Living area (Rural vs Urban (ref)) 48,436/14,587 (30) 1.05 (1.03;1.07)  < 0.001 14,483/5,688 (39) 1.02 (0.99;1.06) 0.191 2,384/888 (37) 1.11 (1.01;1.23) 0.025
Admission (Urgent vs Elective (ref)) 132,233/42,894 (32) 1.35 (1.28;1.42)  < 0.001 32,911/13,549 (41) 2.36 (2.1;2.67)  < 0.001 4,818/1,780 (37) 2.48 (1.88;3.26)  < 0.001
Comorbidities
Diabetes 20,956/7,284 (35) 1.34 (1.3;1.37)  < 0.001 2,217/948 (43) 1.26 (1.18;1.35)  < 0.001 245/82 (33) 1.02 (0.81;1.27) 0.897
Essential hypertension 70,477/17,893 (25) 0.58 (0.57;0.59)  < 0.001 13,919/4,237 (30) 0.55 (0.53;0.57)  < 0.001 1,822/456 (25) 0.47 (0.42;0.52)  < 0.001
Surgery types
Endovascular 3,319/617 (19) 0.63 (0.58;0.69)  < 0.001 810/187 (23) 0.55 (0.48;0.64)  < 0.001 486/ 77 (16) 0.42 (0.33;0.53)  < 0.001
Trepanation and decompression 98/53 (54) 2.3 (1.75;3.01)  < 0.001 2,259/838 (37) 0.87 (0.81;0.94)  < 0.001 64/35 (55) 1.48 (1.05;2.07) 0.023
Neuronavigational operation 16/5 (31) 0.77 (0.32;1.85) 0.56 286/66 (23) 0.49 (0.39;0.64)  < 0.001 8/3 (38) 1.68 (0.54;5.24) 0.369
Shunt and anastomosis 27/16 (59) 1.82 (1.11;2.98) 0.017 147/62 (42) 1.16 (0.9;1.49) 0.244 14/7 (50) 1.55 (0.73;3.26) 0.252
Cardiovascular 538/400 (74) 3.17 (2.88;3.51)  < 0.001 385/222 (58) 1.19 (1.04;1.36) 0.01 30/20 (67) 1.5 (0.96;2.34) 0.073