Table 1.
Formulation | Mass ratio (mg/g of oil) | Molar ratio (mmol/mol of oil) | ||||
---|---|---|---|---|---|---|
PEGylated surfactants | Non-PEGylated surfactants | Polymer | PEGylated surfactants | Non-PEGylated surfactants | Polymer | |
SD-l-PEG-HA | 238 | 20 | 36 | 68.31 | 20.89 | 0.27 |
SD-noPEG-HA | N/A | 73 | 45 | N/A | 86.64 | 0.40 |
SD-noPEG-PSA | N/A | 58 | 34 | N/A | 84.94 | 0.40 |
SE-b-PEG-HA | 265 | 2 | 2 | 105.62 | 2.26 | 0.02 |
SD-noPEG-PEG·PGA | N/A | 35 | 53 | N/A | 22.45 | 3.64 |
SD-l-PEG-HA, lineal-polyethylene glycol-containing hyaluronic acid nanocapsules formulated by solvent displacement; SD-noPEG-HA, non-PEGylated hyaluronic acid nanocapsules formulated by solvent displacement; SD-noPEG-PSA, non-PEGylated polysialic acid nanocapsules formulated by solvent displacement; SE-b-PEG-HA, self-emulsifying branched-polyethylene glycol-containing hyaluronic acid nanocapsules; SD-noPEG-PEG·PGA, solvent displacement nanocapsules with non-PEGylated surfactants and a shell of polyethylene glycol polyglutamic acid; N/A, not applicable