Table 2.
A descriptive analysis of the DEGs that are common to IPF, COVID-19, SCLC, NSCLC, and Colon cancer lung metastases.
| Category | GO ID | Term | P-values | Genes |
|---|---|---|---|---|
| GO Biological Process | GO:0,085,029 | Extracellular matrix assembly | 1.13E-04 | MFAP4;LTBP3;GAS6 |
| GO:0,032,823 | Regulation of natural killer cell differentiation | 1.53E-04 | AXL;GAS6 | |
| GO:1,901,031 | Regulation of response to reactive oxygen species | 2.29E-04 | DHFR;STK26 | |
| GO:2,000,669 | Negative regulation of dendritic cell apoptotic process | 3.19E-04 | AXL;GAS6 | |
| GO:0,032,649 | Regulation of interferon-gamma production | 3.74E-04 | SLC7A5;AXL;GAS6;IL18R1 | |
| GO:0,035,457 | Cellular response to interferon-alpha | 4.25E-04 | AXL;GAS6 | |
| GO:0,048,251 | Elastic fiber assembly | 4.25E-04 | MFAP4;LTBP3 | |
| GO:2,000,668 | Regulation of dendritic cell apoptotic process | 8.28E-04 | AXL;GAS6 | |
| GO:0,000,281 | Mitotic cytokinesis | 9.59E-04 | KIF4A;MYH10;CEP55 | |
| GO:2,000,107 | Negative regulation of leukocyte apoptotic process | 9.91E-04 | AXL;GAS6 | |
| GO Cellular Component | GO:0,005,911 | Cell–cell junction | 9.79E-05 | TMEM47;CEACAM1;CADM1;PTPRM;FLNA;PLPP3;RND1 |
| GO:0,005,902 | Microvillus | 0.001488612 | SLC7A5;MYO1B;MSN | |
| GO:0,005,912 | Adherens junction | 0.001858139 | CEACAM1;PTPRM;PLPP3;RND1 | |
| GO:0,016,323 | Basolateral plasma membrane | 0.003025032 | SLC7A5;CADM1;EPCAM;PLPP3 | |
| GO:0,015,629 | Actin cytoskeleton | 0.00829552 | MYO1B;AXL;FLNA;LPXN;RND1 | |
| GO:0,033,116 | Endoplasmic reticulum-Golgi intermediate compartment membrane | 0.016068342 | SERPINA1;PLPP3 | |
| GO:0,062,023 | Collagen-containing extracellular matrix | 0.017279767 | MFAP4;SERPINA1;ADAMTS1;HDGF;LTBP3 | |
| GO:0,005,658 | Alpha DNA polymerase:primase complex | 0.019596385 | PRIM1 | |
| GO:0,071,953 | Elastic fiber | 0.019596385 | MFAP4 | |
| GO:0,002,189 | Ribose phosphate diphosphokinase complex | 0.019596385 | PRPS2 | |
| GO Molecular Function | GO:0,035,639 | Purine ribonucleoside triphosphate binding | 8.24E-05 | PRPS2;RASL12;RRM1;MYO1B;SNRK;STK26;SCG5;MYH10;RND1 |
| GO:0,005,524 | ATP binding | 8.13E-04 | PRPS2;RRM1;MYO1B;SNRK;STK26;MYH10 | |
| GO:0,042,803 | Protein homodimerization activity | 8.90E-04 | GGCT;PRPS2;CEACAM1;PLN;CADM1;ZBTB16;STK26;RPE;FLNA | |
| GO:0,032,559 | Adenyl ribonucleotide binding | 0.001331367 | PRPS2;RRM1;MYO1B;SNRK;STK26;MYH10 | |
| GO:0,048,027 | mRNA 5'-UTR binding | 0.004357181 | MYH10;CCT5 | |
| GO:0,001,222 | Transcription corepressor binding | 0.005836836 | ZBTB16;HDGF | |
| GO:0,008,374 | O-acyltransferase activity | 0.006237826 | LPCAT1;PLA2G4A | |
| GO:0,015,175 | Neutral amino acid transmembrane transporter activity | 0.00707639 | SLC7A5;SLC1A4 | |
| GO:1,901,981 | Phosphatidylinositol phosphate binding | 0.00769414 | MYO1B;ARAP3;PLA2G4A | |
| GO:0,005,547 | Phosphatidylinositol-3,4,5-trisphosphate binding | 0.008424198 | MYO1B;ARAP3 |