Table 4.
Univariate analysis of included patients by one-year clinical prognosis in general.
| Factors | Effective clinical prognosis (n = 72) | Ineffective clinical prognosis (n = 25) | Exp (B) | 95%CI | p value |
|---|---|---|---|---|---|
| Age (years old), mean ± SD | 50.7 ± 17.3 | 63.1 ± 12.6 | 1.054 | 1.018–1.091 | 0.003 |
| Gender (male, %) | 35 (48.6) | 17 (68.0) | 0.445 | 0.171–1.161 | 0.098 |
| BMI (kg/m2), mean ± SD | 20.8 ± 2.9 | 19.4 ± 3.4 | 0.852 | 0.725–1.001 | 0.052 |
| Duration of illness (> 6 months), n (%) | 37 (51.4) | 11 (44.0) | 0.743 | 0.298–1.856 | 0.525 |
| Hypertension, n (%) | 5 (6.9) | 4 (16.0) | 2.552 | 0.627–10.383 | 0.191 |
| Diabetes mellitus, n (%) | 4 (5.6) | 1 (4.0) | 0.708 | 0.075–6.655 | 0.763 |
| Cardiovascular disease, n (%) | 2 (2.8) | 1 (4.0) | 1.458 | 0.126–16.812 | 0.762 |
| Smoking, n (%) | 15 (20.8) | 8 (32.0) | 1.788 | 0.648–4.933 | 0.262 |
| Drinking, n (%) | 16 (22.2) | 5 (20.0) | 0.875 | 0.284–2.699 | 0.816 |
| Vertebral body involvement | |||||
| Abscess, n (%) | 49 (68.1) | 15 (60.0) | 0.704 | 0.275–1.804 | 0.465 |
| Kyphotic deformity, n (%) | 7 (9.7) | 2 (8.0) | 0.807 | 0.156–4.170 | 0.798 |
| Vertebra collapse, n (%) | 22 (30.6) | 10 (40.0) | 1.515 | 0.589–3.895 | 0.388 |
| Bone destruction, n (%) | 66 (91.7) | 23 (92.0) | 1.045 | 0.197–5.549 | 0.958 |
| Cord compression, n (%) | 30 (41.7) | 10 (40.0) | 0.933 | 0.369–2.359 | 0.884 |
| Involvement of > 2 vertebrae, n (%) | 25 (34.7) | 9 (36.0) | 1.057 | 0.409–2.734 | 0.908 |
| Location of junction lesions, n (%) | 21 (29.2) | 8 (32.0) | 1.143 | 0.428–3.051 | 0.790 |
| Extra-osseous lesions, n (%) | 18 (25.0) | 13 (52.0) | 3.250 | 1.258–8.393 | 0.015 |
| Neurological dysfunction, n (%) | 27 (37.5) | 11 (44.0) | 1.310 | 0.520–3.295 | 0.567 |
| Complications | |||||
| Pneumonia, n (%) | 5 (6.9) | 13 (52.0) | 14.517 | 4.370–48.222 | < 0.001 |
| Sinus tract, n (%) | 2 (2.8) | 3 (12.0) | 4.773 | 0.749–30.421 | 0.098 |
| Incision infection, n (%) | 3 (4.2) | 2 (8.0) | 2.000 | 0.314–12.724 | 0.463 |
| Deep vein thrombosis, n (%) | 2 (2.8) | 0 (0) | < 0.001 | NA | 0.999 |
| Bone graft non fusion, n (%) | 0 (0) | 1 (4.0) | NA | NA | 1.000 |
| Liver injury, n (%) | 1 (1.4) | 2 (8.0) | 6.174 | 0.535–71.266 | 0.145 |
| Lower urinary tract infection, n (%) | 2 (2.8) | 4 (16.0) | 6.667 | 1.140–38.984 | 0.035 |
| Renal failure, n (%) | 0 (0) | 1 (4.0) | NA | NA | 1.000 |
| Serum albumin (g/dL), mean ± SD | 3.8 ± 0.4 | 3.1 ± 0.5 | 0.017 | 0.003–0.097 | < 0.001 |
| Total lymphocytes (/mL), | 1263.6 ± 475.5 | 967.2 ± 449.5 | 0.999 | 0.997–1.000 | 0.012 |
| Total cholesterol (mg/dL), | 90.3 ± 17.4 | 82.7 ± 19.0 | 0.977 | 0.953–1.003 | 0.078 |
| CONUT score, n (%) | 0.644 | 0.532–0.781 | < 0.001 | ||
| Low-CONUT (≤ 5) | 57 (79.2) | 4 (16.0) | |||
| High-CONUT (> 5) | 15 (20.8) | 21 (84.0) | |||
| PNI, n (%) | 2.957 | 1.871–4.673 | < 0.001 | ||
| Low-PNI (≤ 38.6) | 6 (8.3) | 20 (80.0) | |||
| High-PNI (> 38.6) | 66 (91.7) | 5 (20.0) | |||
CONUT controlling nutritional status, PNI prognostic nutrition index, BMI body mass index, SD standard deviation, 95%CI 95% confidence interval, NA not available.