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. 2022 Sep 13;3:932530. doi: 10.3389/fpain.2022.932530

Figure 1.

Figure 1

Myelin oligodendrocyte glycoprotein (MOG) in Sprague-Dawley (SD) rats produces no motor scores at low doses and mild motor scores a higher doses. Sprague-Dawley (SD) rats were baselined (BL) for motor scores followed by intradermal low-dose (0, 4, 8, and 16 μg) myelin oligodendrocyte glycoprotein (MOG). Motor scores were assessed thereafter across the timecourse shown, continuing through day 30. Neither 4 or 8 μg MOG produced motor scores, whereas 16 μg MOG produced mild motor scores. No dose of MOG reliably increased motor scores. N = 5/group.