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Equilibrium binding affinities of PES for PfHsp70-1/PfHsp70-1NBD and PfHop.
| Ligand | Analyte | KD (µM) | χ2 |
|---|---|---|---|
| PfHsp70-1 | PES | 0.0692 ± 0.02 | 1.70 |
| ATP | 0.537 ± 0.07 | 1.73 | |
| PfHop | PES | 0.707 ± 0.07 | 7.31 |
| ATP | 0.861 ± 0.01 | 6.90 | |
| PfHsp70-1NBD | PES | 7.39 ± 0.09 | 9.14 |
| ATP | 0.0223 ± 0.03 | 1.01 |
K D , equilibrium constant, X2 values indicate the goodness of fit for SPR, sensorgrams. Each parameter is the mean for three independent experiments, each performed in triplicate and standard errors of the mean are indicated.
