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. 2022 Sep 13;13:993387. doi: 10.3389/fgene.2022.993387

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Copyright © 2022 Cediel-Ulloa, Yu, Hinojosa, Johansson, Forsby, Broberg and Rüegg.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MED31 DNA methylation and gene expression in MeHg-exposed SH-SY5Y cells; (A) DNA methylation levels at position chr17: 6,555,443 located 3 bp from cg24184221; (B) DNA methylation levels at position chr17: 6,555,742; (C) MED31 expression levels. The results are presented as the mean ± SD of three independent biological replicates and were analyzed with One-way Analysis of variance (ANOVA) with Dunnett’s post-hoc test. Statistical significance was considered when the p-value was below 0.05.