Figure 7.

Effects of TPH1 overexpression on cell viability and CTA level in CTX-TNA2 cells stimulated by H₂O₂.A, TPH1 was successfully overexpressed in CTX-TNA2 cells. B, histogram of TPH1 protein expression. n = 6. C, verification of mRNA level with TPH1 overexpression. n = 4. D, overexpression of TPH1 had no protective effects on CTX-TNA2 cell viability stimulated by H₂O₂. n = 3. E, TPH1 overexpression reversed abnormal CAT decrease induced by H₂O₂. n = 4. Vector group on behalf of empty virus vector. Data are means ± SEM. ∗p < 0.05, ∗∗∗∗ p < 0.0001. Control group data were normalized to 100% and other data were normalized accordingly. CAT, catalase.