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(A) The conservative hydrophobic interactions of CoV N-NTD dimers are shown on the upper left and hydrogen bonds on the lower left (monomer a: green, monomer b: cyan, PDB:4UD1). P3 mediates the homo-polymerization of MERS-CoV N-NTD (right, PDB:6KL6). (B) Diagram of molecular glue P3-mediated polymerization of viral proteins.
