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. 2022 Sep 13;10:976182. doi: 10.3389/fcell.2022.976182

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Copyright © 2022 Kunimoto, Weiner, Axelrod and Vladar.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Basal body orientation in adult Pk mutant multiciliated cells. (A). Basal body misorientation metrics in adult Pk mutants with appropriate statistics. Vangl1CKO ^Δ/Δ and Pk2 ^−/− data were used from (Vladar et al., 2016) with permission. Fraction of correctly oriented basal feet per cell is plotted in the graph (right). Results from a one-way ANOVA are shown in the table (left) as follows: statistically significant p-values are shown in black, nonsignificant p-values are shown in grey, grey "-” indicates tests that are not shown. Vangl1CKO ^Δ/Δ containing genotypes are highlighted in blue. (B). Representative TEM images showing basal foot orientation with respect to tissue axis.