Figure 3.

Effects of once-daily administration of desHis¹Pro⁴Glu⁹-glucagon or desHis¹Pro⁴Glu⁹-glucagon(Lys¹²PAL) (each at 25 nmol/kg bw) for 18 days on oral glucose tolerance in HFF-STZ mice (18 mmol/kg bw). Blood glucose (A) and associated plasma insulin responses (C) with respective areas under the curves (B and D) are provided. Values are mean ± s.e.m. (n = 8). *P < 0.05 compared to HFF-STZ saline controls. ^Ω P < 0.05 compared to HFF saline controls.