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METH inhibits flow mediated dilation and velocity in femoral artery. Representative doppler images from B-mode and pulse wave velocity of FMD from (A) Saline-treated and (B) METH-treated mice flow mediate dilation of femoral artery. Panel C shows quantitation of percent change in vessel diameter, and (D) blood flow velocity in femoral arteries of control and METH-treated mice, respectively. n = 5 per cohort, ##P < 0.001 vs. saline control.
