Table 2. Detection of Vaccine RNA in Whole Expressed Breast Milk and Extracellular Vesicles in 5 Patients at Various Time Points Postvaccination.
Participant No. | Vaccine type | Time points of vaccine mRNA detection in EBM | Concentration of vaccine mRNA detected in whole milka | Concentration of vaccine mRNA detected in EBM EVsa |
---|---|---|---|---|
4 | BNT162b2 | 27-hb Sample | Not detected | 14.01 pg/mL |
6 | mRNA-1273 | 27-h and 42-hb Samples | 11.7 pg/mL | 16.78 pg/mL |
7 | BNT162b2 | 37-hb Sample | Not detected | 4.69 pg/mL |
8 | BNT162b2 | 1-h and 3-hb Samples | 1.3 pg/mL | 6.77 pg/mL |
10 | mRNA-1273 | 45-hb Sample | 2.5 pg/mL | 2.13 pg/mL |
Abbreviation: EBM, expressed breast milk; EVs, extracellular vesicles; mRNA, messenger RNA.
Units for concentration are picogram of mRNA per milliliter of whole milk equivalent.
Sample used for vaccine mRNA concentration detection.