Table 1. Baseline Demographic, Clinical, and Treatment Data.
| Characteristic | Patients, No. (%) | P value | |
|---|---|---|---|
| General anesthesia (n = 43) | Conscious sedation (n = 44) | ||
| Age, mean (SD), y | 64 (11) | 60 (13) | .07 |
| Female | 10 (23.3) | 6 (13.6) | .25 |
| Male | 33 (76.7) | 38 (86.4) | |
| BMI, mean (SD)a | 26 (3) | 26 (3) | .80 |
| Medical history | |||
| Hypertension | 32 (74.4) | 31 (70.5) | .68 |
| Atrial fibrillation | 7 (16.3) | 7 (15.9) | .96 |
| Coronary artery disease | 6 (14.0) | 7 (15.9) | .80 |
| Dyslipidemia | 17 (39.5) | 14 (31.8) | .45 |
| Diabetes | 13 (30.2) | 10 (22.7) | .43 |
| Transient ischemic attack | 5 (11.6) | 4 (9.1) | .97 |
| Past stroke | 9 (20.9) | 7 (15.9) | .55 |
| Smoking | 24 (55.8) | 29 (65.90) | .34 |
| Drinking | 11 (25.6) | 17 (38.6) | .19 |
| Etiology | |||
| Cardiogenic thrombosis | 8 (18.6) | 9 (20.5) | .83 |
| Atherosclerosis | 35 (81.4) | 35 (79.5) | |
| Drug use | |||
| Antiplatelet agent | 12 (27.9) | 12 (27.3) | .95 |
| Anticoagulant agent | 2 (4.7) | 3 (6.8) | .66 |
| Statin | 10 (23.3) | 10 (22.7) | .95 |
| Hypoglycemic agent | 9 (20.9) | 8 (18.2) | .75 |
| ASA class, median (IQR) | 3 (3-4) | 3 (3-4) | .90 |
| Premorbid modified Rankin Scale score, median (IQR) | 0 (0-1) | 0 (0-0) | .28 |
| Clinical status at admission | |||
| Modified Rankin Scale score, median (IQR) | 4 (4-5) | 4 (4-4) | .58 |
| NIHSS score, median (IQR) | 16 (12-21) | 15 (12-18) | .69 |
| Glasgow Coma Scale score, median (IQR) | 11 (10-12) | 12 (9-14) | .36 |
| Systolic blood pressure, mean (SD), mm Hg | 160 (21) | 161 (22) | .83 |
| Arterial pressure, mean (SD), mm Hg | 113 (14) | 113 (15) | .97 |
| Lesion location | |||
| Basilar artery | 9 (20.9) | 12 (27.3) | .72 |
| Vertebral artery V4 segment | 27 (62.8) | 24 (54.5) | |
| Basilar artery combined V4 | 7 (16.3) | 8 (18.2) | |
| IV-tPA pretreatment | 7 (16.3) | 5 (11.4) | .51 |
| Time interval, median (IQR), min | |||
| Onset to door | 210 (90-390) | 300 (151-450) | .14 |
| Onset to operating room | 400 (270-570) | 448 (313-716) | .39 |
| Onset to puncture | 415 (290-586) | 467 (330-731) | .45 |
| Onset to reperfusion | 524 (405-717) | 562 (416-819) | .63 |
| Door to puncture | 185 (150-255) | 151 (108-214) | .08 |
| Operating room to puncture | 20 (15-30) | 15 (10-22) | .003 |
| Door to reperfusion | 284 (240-337) | 237 (189-340) | .05 |
| Operating room to reperfusion | 125 (96-140) | 94 (75-135) | .02 |
| Puncture to reperfusion | 99 (68-118) | 81 (55-116) | .15 |
| Operating time | 125 (98-145) | 105 (71-135) | .07 |
Abbreviations: ASA, American Society of Anesthesiologists physical status classification; BMI, body mass index; IV-tPA, intravenous alteplase; NIHSS, National Institute of Health Stroke Scale.
a
Calculated as weight in kilograms divided by height in meters squared.