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. 2022 Aug 22;20:5296–5308. doi: 10.1016/j.csbj.2022.08.007

Table 2.

Test performance of each method.

HML (Approach 1) HML (Approach 2) CART Random forest
Sensitivity 0.574 ± 0.079 0.765 ± 0.011 0.682 ± 0.024
(p=0.003)1
0.725 ± 0.012
(p=0.231)1
Specificity 0.848 ± 0.036 0.825 ± 0.008 0.806 ± 0.011
(p=0.221)1
0.834 ± 0.005
(p=0.685)1
Precision 0.694 ± 0.055 0.695 ± 0.010 0.658 ± 0.011
(p=0.014)1
0.705 ± 0.005
(p=0.710)1
Accuracy 0.760 ± 0.037 0.792 ± 0.006 0.760 ± 0.008
(p=0.002)1
0.795 ± 0.003
(p=0.956)1
F1 0.610 ± 0.039 0.721 ± 0.008 0.663 ± 0.015
(p<0.001)1
0.713 ± 0.006
(p=0.853)1
# of leaf nodes 3.8 ± 1.095 4.2 ± 0.236 26.2 ± 2.145
(p<0.001)2

Each value shows mean ± SE of performances obtained from 5-fold CV.

1Tukey's HSD tests were performed on three groups: HML (Approach 2), CART, and random forest, and the p-value between HML and the corresponding algorithm is shown.

2The p-value between HML (Approach 2) and CART by Student's t-test is shown.