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Effect of dry eye drugs on immortalized epithelial cell cultures. Immortalized epithelial cell cultures treated with (A) tacrolimus 0.03%, (B) tacrolimus 0.1%, (C) lifitegrast, and (D) cyclosporine for 30 seconds, 1 minute, 1 hour, and 4 hours. Cell survival was analyzed using the XTT assay after 72 hours and normalized to treatments with saline.
