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HLAII-presented sequences derived from anti-TNF compounds identified by HLAII immunopeptidomics. (A, B) Sequence coverage of identification within both light chain (LC) and heavy chain (HC) from antagonists detected in HLAII immunopeptidomes from antagonist-treated sets corresponding to INFL (blue) ADAL (green) and Fab’ (orange) (C) Length distribution of identified TNF antagonist-derived peptides from all donors.
