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. Author manuscript; available in PMC: 2023 Aug 18.
Published in final edited form as: Cell Chem Biol. 2022 Jul 12;29(8):1303–1316.e3. doi: 10.1016/j.chembiol.2022.06.006

Figure 6: Antiviral activity of JG compounds in distinct host cells.

Figure 6:

(A-C) Effect of JG compounds on DENV productivity and cell viability in mammalian Huh7 (A) and mosquito C6/36 (B) cells. Each virus productivity was shown as square and dashed line (left Y axis) and cell viability as circle and solid line (right Y-axis). X-axis: drug concentration (0.56, 1,66 and 5 μM). (C) Heat map illustrating anti DENV effect in Huh7(i) and C6/36(ii). Highly toxic JG compounds showed as grey color. (D) The comparison of two distinct activities of JG compounds. Anti-cancer activity in MDA-MB-231 cells (red circles, left axis) and anti-DENV activity in Huh7(blue circles, right axis) were shown with EC50.The data shown are average of three independent experiments.