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. 2022 Sep 27;23:390. doi: 10.1186/s12859-022-04951-0

Fig. 5.

Fig. 5

Methylation analysis of collagen VI family in pan-cancer. A Differential methylation levels of COL6A1/2/3 between TCGA cancers and adjacent normal tissues. Blue and red dots represent down-regulation and up-regulation of methylation in tumors, and the darker the dots, the greater the differences. The size of the dots indicates statistical significance. B Correlation between methylation levels and expression levels of COL6A. Blue and red represent negative correlation and positive correlation, respectively. C Effects of hypermethylation of COL6A on the overall survival risk. Red dots represent high risk, while blue dots represent low risk. The size of the dots indicates statistical significance