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. 2022 Sep 27;21:274. doi: 10.1186/s12936-022-04296-2

Table 5.

Determinants of injectable antimalarial treatment for severe malaria at referral health facilities in community enrolments

Determinants N % Adjusted OR 95% CI p value
Age
 Children (0–2 years) 921 61.0 Ref.
 Children (2–5 years) 590 39.0 1.13 0.78–1.63 0.53
Enrolment location
 CHW 40 2.7 Ref.
 PHC 1471 97.4 0.57 0.17–1.91 0.36
Health Zone
 Ipamu 716 47.4 Ref.
 Kenge 500 33.1 6.30 3.30–12.05 < 0.001
 Kingandu 295 19.5 0.83 0.48–1.44 0.51
Danger signs
 No/Others 271 17.9 Ref.
 Yes (iCCM general danger signs) 1049 69.4 1.12 0.70–1.78 0.64
 Weakness or asthenia 68 4.5 1.16 0.45–2.98 0.76
 Unable to sit 123 8.1 1.39 0.61–3.13 0.43
RAS administration
 No 220 14.6 Ref.
 Yes 1291 85.4 4.75 3.00–7.52 < 0.001
Referral delay
 0–1 day 1066 70.6 Ref.
 > 1 day/Not documented 445 29.4 1.05 0.71–1.55 0.81
Malaria test result (RHF)
 Positive 1227 81.2 Ref.
 Negative/Not done 284 18.8 0.07 0.04–0.11 < 0.001
Anaemia at arrival at RHF
 No/mild anaemia/not done 726 48.1 Ref.
 Severe anaemia (≤ 5 g/dL) 785 52.0 2.28 1.38–3.77 0.001
Other comorbidities
 No 802 53.1 Ref.
 Yes 709 46.9 2.36 1.62–3.44 < 0.001
Blood transfusion
 Yes 775 51.29 Ref.
 No 736 48.71 0.53 0.32–0.87 0.01

N = 1511. OR: Odds ratio; CHW: Community Health Worker; PHC: Primary Health Care; RHF: Referral Health Facilities; RAS: rectal artesunate; 95% CI: 95% confidence intervals