Table 7.
Determinants of death within 28 days following enrolment
| Determinants | N | % | Adjusted OR | 95% CI | p value |
|---|---|---|---|---|---|
| Age | |||||
| Children (0–2 years) | 1255 | 57.6 | Ref. | ||
| Children (2–5 years) | 923 | 42.4 | 0.44 | 0.29–0.65 | < 0.001 |
| Health Zone | |||||
| Ipamu | 845 | 38.8 | Ref. | ||
| Kenge | 749 | 34.4 | 0.66 | 0.35–1.24 | 0.19 |
| Kingandu | 584 | 26.8 | 0.78 | 0.41–1.50 | 0.45 |
| iCCM danger signs | |||||
| No/Others | 415 | 19.1 | Ref. | ||
| Yes (iCCM general danger signs) | 1614 | 74.1 | 1.57 | 0.94–2.61 | 0.08 |
| Unable to sit | 149 | 6.8 | 0.14 | 0.02–1.13 | 0.07 |
| RAS administration | |||||
| No | 308 | 14.1 | Ref. | ||
| Yes | 1870 | 85.9 | 1.50 | 0.86–2.60 | 0.15 |
| Malaria test (RHF) | |||||
| Negative/Not done | 999 | 45.9 | Ref. | ||
| Positive | 1179 | 54.1 | 1.89 | 0.98–3.65 | 0.06 |
| Anaemia on arrival at RHF | |||||
| No/mild anaemia/not done | 1430 | 65.7 | Ref. | ||
| Anaemia (Hb < 5 g/dL) | 748 | 34.3 | 2.13 | 1.22–3.69 | 0.008 |
| Other comorbidities | |||||
| No | 1501 | 68.9 | Ref. | ||
| Yes | 677 | 31.1 | 1.13 | 0.67–1.91 | 0.64 |
| Injectable antimalarial | |||||
| No/NA | 970 | 44.5 | Ref. | ||
| Yes | 1208 | 55.5 | 2.07 | 0.72–5.95 | 0.18 |
| Oral antimalarial given at RHF | |||||
| No | 1076 | 49.4 | Ref. | ||
| Yes | 1102 | 50.6 | 0.13 | 0.07–0.26 | < 0.001 |
| Oral treatment given at discharge or prescribed | |||||
| No/NA | 1499 | 68.8 | Ref. | ||
| Yes | 679 | 31.2 | 0.53 | 0.25–1.13 | 0.10 |
| Injectable antimalarial & ACT | |||||
| No | 920 | 42.2 | Ref. | ||
| Yes | 1258 | 57.8 | 0.26 | 0.09–0.79 | 0.018 |
N = 2178. OR: Odds ratio; CHW: Community Health Worker; iCCM: integrated Community Case Management; PHC: Primary Health Care; RHF: Referral Health Facility; RAS: rectal artesunate; 95% CI: 95% confidence intervals; ACT: artemisinin-based combination therapy; Hb: Haemoglobin; NA: not applicable