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. 2022 Sep 27;15(11):104302. doi: 10.1016/j.arabjc.2022.104302

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Fig. 7 — A 3D organoid culture system for mimicking hyperuricemia (HUA) in vitro was established using cultured human liver organoids. The organoid model was verified by measuring the antihyperuricemic effect of the widely used allopurinol, as well as the reported bioactive substance puerarin from TCM (Hou et al., 2022). Reprinted with permission from Ref. Hou et al., 2022. Copyright © 2021 Elsevier.