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. Author manuscript; available in PMC: 2022 Sep 27.
Published in final edited form as: J Biomed Nanotechnol. 2019 Nov 1;15(11):2229–2239. doi: 10.1166/jbn.2019.2859

Figure 3. CTLA-4 Nb16 increased the abundance of IFN-γ secreting CD8+ T lymphocytes.

Figure 3.

(A) CD8+ cells were mixed with different antibodies following with DHFC, and then co-cultured for 7 days. ELISPOT assay was applied to examine the number of CD8+ T lymphocytes secreting IFN-γ. (B) The number of spots in DHFC+CTLA-4 Nb16 group increased significantly than other’s groups, except DHFC+CTLA-4 mAb groups. Data are means ± SD, n = 3. *** P < 0.001, **** P < 0.0001.