Date	Event	Description
4 November 2021	New search has been performed	The review has been updated. We conducted a new search in November 2021. We include 5 new studies (Ashfaq 2018; Behnoud 2019; Najafi 2020; Salazar‐Ortiz 2016; Shi 2019). We added 6 new studies to awaiting classification (NCT03664050; NCT02703649; Jindal 2019; ,Ghoneim 2020; Kamel 2019; Rezk 2018). We added 5 studies as ongoing (CTRI/2018/04/013343; Cutler 2018; Huang 2020; IRCT2016030926962N2; Priest 2019). 4 studies that were included in the previous version have been excluded due to concerns about validity of the study data (study retraction or expression of concern) (Abu Hashim 2010; Badawy 2008; Badawy 2009a; Badawy 2009b). 2 studies that were included in the previous version have been moved to awaiting classification due to concerns about validity of the study data (Abdellah 2011; Abu Hashim 2010a).
4 November 2021	New citation required but conclusions have not changed	The addition of new studies has not led to a change in conclusions.