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. 2022 Sep 27;2022(9):CD010287. doi: 10.1002/14651858.CD010287.pub4

Aygen 2007.

Methods Randomised clinical trial
Participants 15 infertile women with PCOS
Interventions Women were randomised into 3 treatment groups:
Group 1: continuous metformin was used at the dose of 850 mg/tid/day for 6 months; afterwards, daily 2.5 mg letrozole between 3 and 7 days of the menstrual cycle was added to the metformin therapy.
Group 2: participants received only daily 2.5 mg letrozole between days 3 and 7 of the menstrual cycle.
Group 3: participants received daily 100 mg CC only between days 3 and 7 of the menstrual cycle.
Outcomes Unclear
Notes The article was written in Turkish, and we were not able to have it translated properly.