TABLE 3.
Connection between α1 and α2 | Classification | SURP‐containing protein | SURP domain | Type‐specific residues | A binding protein |
---|---|---|---|---|---|
G‐bend | Type 1a a | SF3A1 | SURP1 | ||
SFSWAP | SURP2 | R62, N63, K80 b | SF1 | ||
CHERP | SURP | ||||
Type 1b | SFSWAP | SURP1 | – c | – | |
SR140 | SURP | – | – | ||
SF4 | SURP1 | – | – | ||
SF4 | SURP2 | – | – | ||
SFRS14 | SURP2 | – | – | ||
Type 2 | SF3A1 | SURP2 | F162, L169 | SF3A3 | |
Loop | Type 3 | SFRS14 | SURP1 | – | – |
Currently, Type‐1 SURP domains are divided into two subtypes, depending on whether they can bind to SF1.
The residue number is according to SF3A1 SURP1.
“–” refers to “unknown.”