Figure 2.
Comparison of Br512 and Bst-LF in LAMP-OSD assays of DNA templates. LAMP-OSD assays for the human GAPDH gene were carried out with 20 pmol of in-house purified Bst-LF (panel A) or 20 pmol of Br512 (panel B) in the indicated reaction buffer. Amplification curves were observed in real-time at 65 °C by measuring OSD fluorescence in reactions seeded with 600,000 (black traces), 60,000 (red traces), 6000 (blue traces), 600 (pink traces), and 0 (gray traces) copies of GAPDH plasmid templates.