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. Author manuscript; available in PMC: 2022 Sep 27.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2020 Jun 10;29(7):1304–1312. doi: 10.1158/1055-9965.EPI-19-1534

Table 3.

Cancer-attributable annualized average costs* in 2019 US dollars for medical services (Medicare Parts A & B) and oral prescription drugs (Medicare Part D) by cancer site, phase of care and stage of disease at diagnosis.

Medical Services Costs in 2019 Thousand dollars
Initial
Continuing
EOL-cancer
Site Local# Regional Distant Local Regional Distant Local Regional Distant
Bladder $19.4 $64.8 $86.1 $5.7 $9.1 $14.4 $73.3 $104.9 $139.4
Breast $30.4 $50.7 $67.4 $2.9 $5.2 $22.3 $65.7 $72.0 $91.9
Cervix Uteri $41.1 $66.3 $78.2 $2.7 $4.4 $15.4 $77.9 $92.2 $111.0
Colorectal $46.4 $78.9 $125.8 $4.6 $6.8 $31.4 $89.1 $100.9 $126.7
Esophagus $74.7 $103.4 $94.7 $9.0 $8.2 $19.2 $101.5 $122.0 $120.5
Kidney $35.2 $47.5 $70.5 $7.7 $9.1 $20.0 $81.3 $87.8 $112.5
Liver $60.7 $63.2 $72.3 $17.6 $19.3 $11.9 $81.9 $89.9 $116.4
Lung $51.4 $70.6 $88.1 $8.9 $12.1 $26.2 $80.5 $95.6 $123.1
Lung-NSC $51.0 $69.7 $87.8 $8.9 $12.0 $27.3 $80.3 $94.7 $123.4
Lung-SC $67.0 $80.8 $89.6 $11.6 $13.7 $17.5 $84.6 $102.1 $121.4
Melanoma $8.8 $28.9 $60.9 $2.8 $6.5 $15.5 $65.6 $75.3 $119.2
Oral Cavity $30.2 $77.0 $88.4 $4.8 $6.3 $8.1 $86.1 $108.4 $123.3
Ovary $44.2 $67.4 $86.6 $2.7 $9.0 $21.9 $79.8 $92.5 $111.3
Pancreas $79.8 $121.7 $101.1 $11.4 $18.5 $33.6 $104.5 $119.9 $130.4
Prostate# - $26.8 $33.0 - $2.3 $14.4 - $69.0 $78.7
Stomach $62.5 $103.7 $96.8 $5.6 $7.0 $17.1 $100.9 $120.4 $132.8
Thyroid $18.3 $30.9 $61.8 $3.6 $4.2 $9.2 $83.7 $104.6 $122.1
Uterus $29.5 $53.4 $75.5 $2.4 $5.1 $9.7 $80.6 $86.5 $110.9

Oral Prescription Drug Costs in 2019 Thousand dollars
Initial
Continuing
EOL-cancer
Site Local# Regional Distant Local Regional Distant Local Regional Distant
Bladder $0.6 $0.7 $0.9 $0.6 −$0.1 −$0.2 $2.0 $0.7 $1.3
Breast $1.1 $1.6 $1.7 $0.8 $1.2 $2.3 $2.8 $2.8 $2.7
Cervix Uteri −$0.2 −$0.5 −$0.7 −$0.4 −$1.0 −$0.8 $2.9 $0.3 −$0.4
Colorectal $0.4 $0.4 $1.1 $0.3 $0.1 $0.5 $1.3 $1.3 $1.6
Esophagus $1.4 $1.0 $2.9 $1.0 $0.0 $1.2 $1.0 $0.7 $1.4
Kidney $1.2 $1.7 $20.0 $1.5 $2.7 $13.0 $7.9 $11.2 $16.8
Liver $7.1 $12.6 $18.6 $7.1 $8.8 $10.1 $10.9 $14.5 $13.4
Lung $2.0 $2.5 $7.7 $1.8 $2.6 $6.9 $3.9 $4.2 $5.0
Lung-NSC $2.0 $2.5 $8.4 $1.9 $2.7 $7.7 $4.0 $4.5 $5.7
Lung-SC $2.1 $2.2 $2.5 $1.0 $1.2 $1.1 $1.7 $2.0 $1.8
Melanoma $0.6 $1.8 $2.1 $0.4 $0.7 $0.6 $3.5 $3.5 $3.9
Oral Cavity $0.6 $0.4 $0.5 $0.3 −$0.2 $0.0 $1.4 $0.6 $1.3
Ovary $0.4 $0.8 $1.4 $0.1 −$0.2 $0.3 $1.9 $0.7 $1.0
Pancreas $3.0 $4.8 $9.0 $2.7 $3.6 $7.0 $3.9 $5.4 $7.0
Prostate# - $0.3 $1.5 - $0.3 $4.5 - $5.5 $6.8
Stomach $3.8 $1.7 $5.5 $2.1 $1.5 $10.5 $2.1 $1.5 $2.0
Thyroid $0.9 $0.7 $3.4 $0.8 $1.0 $3.4 $7.9 $5.7 $3.2
Uterus $0.1 $0.2 $0.9 $0.0 $0.0 −$0.1 $1.5 $0.9 $1.3
*

Costs calculated from 2007–2013 Medicare claims for patients diagnosed with cancer between 2000 and 2012 and 65 years or older. Phases of care are: initial, first 12 months after each diagnosis; end-of-life (EOL), the 12 months before death, and the continuing, the months in-between the initial and the EOL phases.

#

We used the SEER historical stage that classifies solid tumors into localized, regional and distant. For prostate cancer historical stage classifies tumors into local/regional versus distant.

AML= Acute Myeloid Leukemia; CLL= Chronic Lymphocytic Leukemia; CML= Chronic Myeloid Leukemia; NSC=Non-Small Cell; SC= Small Cell.