TABLE 3.
Univariate and Multivariate Analyses for Variables Associated With Unfavorable Outcomes (mRS 3-6) Before and After Propensity Score Analysis
| Variable | Univariate | Univariate after propensity score analysis | Multivariate after propensity score analysis | ||||||
|---|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | P-value | OR | 95% CI | P-value | OR | 95% CI | P-value | |
| Sex (female) | 0.9 | 0.6-1.5 | .736 | ||||||
| Increasing age | 1.0 | 1.0-1.0 | .012 | 1.0 | 1.0-1.0 | .038 | 1.0 | 1.0-1.1 | .016 |
| COVID-19 | 1.9 | 1.2-3.1 | .004 | 2.5 | 1.3-5.1 | .008 | 2.6 | 1.1-5.8 | .025 |
| NIHSS at admission | 1.1 | 1.1-1.1 | <.001 | 1.1 | 1.1-1.2 | <.001 | 1.1 | 1.0-1.1 | .005 |
| Baseline functional status | 1.6 | 1.1-2.4 | .011 | 2.3 | 1.1-4.9 | .026 | |||
| Chronic heart disease | 0.8 | 0.5-1.5 | .619 | ||||||
| Chronic lung disease | 0.9 | 0.5-1.6 | .821 | ||||||
| Chronic kidney disease | 1.5 | 0.6-3.5 | .348 | ||||||
| Chronic liver disease | 2.6 | 0.6-11.7 | .205 | ||||||
| Hypertension | 1.4 | 0.8-2.2 | .186 | ||||||
| Diabetes mellitus type II | 1.4 | 0.8-2.4 | .180 | 2.5 | 1.2-5.5 | .019 | |||
| Atrial fibrillation | 0.8 | 0.5-1.3 | .359 | ||||||
| ASPECTS | 0.8 | 0.7-0.9 | .002 | 0.7 | 0.6-0.9 | .005 | |||
| No. of vessels involved | 1.1 | 0.7-1.7 | .578 | ||||||
| LVO location (anterior circulation) | 1.2 | 0.5-2.8 | .682 | ||||||
| Tissue plasminogen activator | 0.8 | 0.5-1.2 | .267 | ||||||
| Onset to door | 1.0 | 0.9-1.0 | .280 | 1.0 | 1.0-1.0 | .045 | |||
| Onset to arterial access | 0.9 | 0.9-1.0 | .031 | 1.0 | 1.0-1.0 | .035 | |||
| General ET intubation | 0.8 | 0.5-1.4 | .448 | ||||||
| Stenting | 0.9 | 0.5-1.9 | .908 | ||||||
| Procedure duration | 1.0 | 0.9-1.0 | .053 | ||||||
| TICI 2B-3 | 0.4 | 0.2-0.8 | .009 | 0.6 | 0.4-0.9 | .015 | 0.6 | 0.4-1.0 | .042 |
ASPECTS, Alberta Stroke Program Early Computed Tomography Score; COVID-19, coronavirus disease; ET, endotracheal; LVO, large vessel occlusion; NIHSS, National Institutes of Health Stroke Scale; OR, odds ratio; TICI, thrombolysis in cerebral infarction.
Bold values indicate statistically significant value P < .05