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. 2022 Mar 7;90(6):725–733. doi: 10.1227/neu.0000000000001902

TABLE 3.

Univariate and Multivariate Analyses for Variables Associated With Unfavorable Outcomes (mRS 3-6) Before and After Propensity Score Analysis

Variable Univariate Univariate after propensity score analysis Multivariate after propensity score analysis
OR 95% CI P-value OR 95% CI P-value OR 95% CI P-value
Sex (female) 0.9 0.6-1.5 .736
Increasing age 1.0 1.0-1.0 .012 1.0 1.0-1.0 .038 1.0 1.0-1.1 .016
COVID-19 1.9 1.2-3.1 .004 2.5 1.3-5.1 .008 2.6 1.1-5.8 .025
NIHSS at admission 1.1 1.1-1.1 <.001 1.1 1.1-1.2 <.001 1.1 1.0-1.1 .005
Baseline functional status 1.6 1.1-2.4 .011 2.3 1.1-4.9 .026
Chronic heart disease 0.8 0.5-1.5 .619
Chronic lung disease 0.9 0.5-1.6 .821
Chronic kidney disease 1.5 0.6-3.5 .348
Chronic liver disease 2.6 0.6-11.7 .205
Hypertension 1.4 0.8-2.2 .186
Diabetes mellitus type II 1.4 0.8-2.4 .180 2.5 1.2-5.5 .019
Atrial fibrillation 0.8 0.5-1.3 .359
ASPECTS 0.8 0.7-0.9 .002 0.7 0.6-0.9 .005
No. of vessels involved 1.1 0.7-1.7 .578
LVO location (anterior circulation) 1.2 0.5-2.8 .682
Tissue plasminogen activator 0.8 0.5-1.2 .267
Onset to door 1.0 0.9-1.0 .280 1.0 1.0-1.0 .045
Onset to arterial access 0.9 0.9-1.0 .031 1.0 1.0-1.0 .035
General ET intubation 0.8 0.5-1.4 .448
Stenting 0.9 0.5-1.9 .908
Procedure duration 1.0 0.9-1.0 .053
TICI 2B-3 0.4 0.2-0.8 .009 0.6 0.4-0.9 .015 0.6 0.4-1.0 .042

ASPECTS, Alberta Stroke Program Early Computed Tomography Score; COVID-19, coronavirus disease; ET, endotracheal; LVO, large vessel occlusion; NIHSS, National Institutes of Health Stroke Scale; OR, odds ratio; TICI, thrombolysis in cerebral infarction.

Bold values indicate statistically significant value P < .05