TABLE 3.
Univariate Cox Proportional Hazards Models for Variables Considered A Priori
| Variable | HR | 95% CI | P-value |
|---|---|---|---|
| Agea | 1.26 | 1.10-1.46 | .001 |
| EOR of CE tissueb | 0.91 | 0.84-0.99 | .040 |
| EOR of NCE tissueb | 0.94 | 0.88-0.99 | .040 |
| Residual CE volumec | 1.27 | 1.04-1.55 | .020 |
| Residual NCE volumed | 1.03 | .98-1.08 | .210 |
| New postoperative impairment | |||
| One or more | 1.87 | 1.38-2.53 | <.0001 |
| Cognitive | 1.51 | 1.15-2.00 | .003 |
| Aphasia | 1.12 | 0.61-2.06 | .72 |
| Visual | 1.48 | 1.08-2.04 | .016 |
| Hemiparesis | 3.83 | 2.20-6.68 | <.0001 |
| Postoperative KPSd | 0.84 | 0.73-0.97 | .0154 |
| Change in KPSd | 0.90 | 0.72-1.13 | .37 |
CE, contrast-enhanced; EOR, extent of resection; KPS, Karnofsky Performance Status; NCE, non–contrast-enhanced
a
Per 10-yr increase.
b
Per 10% increase.
c
Per 10-mL increase.
d
Per 10-point increase.