Table 2.

A Practical Classification of the Main Pediatric NRSTS Histotypes

Adult-type NRSTS requiring the same therapeutic approach Synovial sarcoma Malignant peripheral nerve sheath tumor Adult-type fibrosarcoma Epithelioid sarcoma Leiomyosarcoma Liposarcoma Angiosarcoma Undifferentiated high-grade pleomorphic sarcoma

Adult-type NRSTS requiring a specific therapeutic approach Alveolar soft part sarcoma Clear cell sarcoma Dermatofibrosarcoma protuberans

Malignant soft tissue tumors requiring a specific therapeutic approach Rhabdoid tumor Desmoplastic small round cell tumor Undifferentiated soft part sarcoma Undifferentiated sarcoma of the liver BCOR family/CIC-rearranged undifferentiated sarcomas

Soft tissue tumors of intermediate malignancy requiring specific therapeutic approaches Desmoid-type fibromatosis Infantile fibrosarcoma Inflammatory myofibroblastic tumors Epithelioid hemangioendothelioma