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. 2022 May 2;49(10):9767–9781. doi: 10.1007/s11033-022-07468-0

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Fig. 1 — The PI3K/AKT pathway plays a critical role in the regulation of cardiomyocyte function, as well as the regulation of their growth and survival. This figure shows the role of PI3K/AKT-modulating pathway in the pathoetiology of myocardial ischemia/reperfusion (I/R) injury and myocardial infarction (MI), heart failure, cardiac hypertrophy, cardiomyopathy and toxins-induced cardiac injury