Table 3.

lncRNA expression, targets and effects on RM

lncRNA	Expression	Target	Effect	Refs
H19	Downregulated	miRNA let-7/ITGB3	Inhibits the adhesion and invasion of HTR-8 cell	[43]
Lnc-49a	Downregulated	CD49a	Inhibits the Migration, adhesion, and cytotoxic Activity of dNK cells	[46]
Lnc-SLC4A1-1	Upregulated	NF-κB/CXCL8	Induces immune responses in trophoblast cells	[47]
LncRNA SNHG7-1	Downregulated	miR-34a/WNT1	Inhibits proliferation and invasion of trophoblast cells	[48]
LncRNA HOTAIR	Downregulated	PIK3-AKT signalling pathway	Inhibits the migration and invasion of trophoblast cells	[49]
Lnc-HZ08	Upregulated	PI3K/p-AKT/P21/CDK2 pathway	Inhibits proliferation, migration, and invasion of trophoblast cells	[52]
Lnc-HZ01	Upregulated	MXD1/METTL14	Inhibits proliferation of trophoblast cells	[53]
H19	Downregulated	miR-675	Inhibits proliferation of trophoblast cells	[54]

lncRNA long non‑coding RNA, ITGB3 inhibit integrin β3, HOTAIR HOX antisense intergenic RNA, CXCL8 C-X-C motif ligand 8, WNT1 Wnt Family Member 1, METTL14 Methyltransferase-like 14