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Effect of ASP5736 (0.01 and 0.1 mg/kg, po) on hyperactivity across 60 minutes. Wild-type and vehicle-treated Fmr1-knockout (KO) rats were administered 0.5% methyl cellulose instead of ASP5736. Values are mean ± SEM. Values in parentheses indicate the number of rats in each group. *P < .05, compared with vehicle of Fmr1-KO rats (Dunnett’s multiple comparisons test).
