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. 2022 Jul 26;25(9):786–793. doi: 10.1093/ijnp/pyac041

Figure 3.

Figure 3.

Effect of ASP5736 (0.01 mg/kg, po) on the novel object recognition task (NORT). Wild-type rats and vehicle-treated Fmr1-knockout (KO) rats were administered 0.5% methyl cellulose instead of ASP5736. ASP indicates ASP5736. (A) Time (seconds) each group spent exploring the novel and familiar objects. Values are mean ± SEM. A total of 13 (wild-type group), 14 (vehicle of Fmr1-KO group), and 15 (0.01 mg/kg group) rats were used. *P < .05, **P < .01, statistically significant compared with the familiar object (ANOVA followed by Turkey’s test). (B) Exploratory preference (%) in each group. Values are mean ± SEM. A total of 13 (wild-type group), 14 (vehicle of Fmr1-KO group), and 15 (0.01 mg/kg group) rats were used. **P < .01, statistically significant compared with vehicle-treated Fmr1-KO rats (ANOVA followed by Turkey’s test).