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Effect of intranasal administration of sulforaphane (SF)-loaded within iron oxide nanoparticles (N.SF) or free sulforaphane (SF) on thermal sensitivity: tail-flick test in CIS-induced rats. Groups: negative control rats, cisplatin (CIS)-exposed rats, N.SF-alone exposed rats, CIS + N.SF-treated rats, and CIS + SF-treated rats. Results are presented as mean ± standard error of the mean (SEM). Mean with different letters (a–c) is significant at p ≤ 0.05
